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LONDON, July 26 (Reuters) - GlaxoSmithKline is swimming against the tide by getting out of treatments for rare diseases at a time when rivals like Sanofi and Shire see the field as a rich seam for profits.<br><br>Successful medicines for rare conditions are potentially very lucrative, since prices frequently run into hundreds of thousands of dollars, but patient numbers can be extremely low.<br><br>New GSK Chief Executive Emma Walmsley announced the strategic review and potential divestment of rare diseases on Wednesday as part of a wide-ranging drive to streamline pharmaceutical operations.<br><br>It follows a less than impressive experience for GSK in the field, including the fact that its pioneering gene therapy Strimvelis only secured its first commercial patient in March, 10 months after it was approved for sale in Europe in May 2016.<br><br>Since then a second patient has also been treated and two more are lined up to receive the therapy commercially, a spokesman said.<br><br>Strimvelis, which GSK developed with Italian scientists, is designed for a tiny number of children with ADA Severe Combined Immune Deficiency (ADA-SCID). SCID is sometimes known as "bubble baby" disease, since those born with it have immune systems so weak they must live in germ-free environments.<br><br>If you have any inquiries about in which and how to use bubble shooter pet, you can make contact with us at the site. The new treatment became the first life-saving gene therapy for children when it was approved last year, marking a step forward for the emerging technology to fix faulty genes.<br><br>Walmsley said GSK was not giving up on gene and cell therapy entirely. Research will be focused in future in areas with larger potential patient numbers, including oncology. (Reporting by Ben Hirschler; Editing by Adrian Croft)
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Reef tanks are usually kept at a temperature between 25 and 27 C (75-80 F).  If you have any concerns about in which and how to use bubble shooter pet, you can speak to us at our web site. Reef tanks are beautiful and exotic and for some of us a piece of nature. <br><br>The mainly filtration for reef tanks usually comes from the use of great amounts of live rock which come from various rubble zones around existing reefs. Researchers and scientists find that saltwater fish tank have therapeutic health benefits. The tanks are usually constructed from either glass or acrylic.<br><br>With advances in modern tanks it's recently became possible to have a piece of coral reef at home and enjoy it in the privacy of your house without getting wet with saltwater aquarium. A reef aquarium or reef tank is an aquarium containing live corals and other invertebrates(such as snails) associated with coral reefs. Unlike the marine aquarium, the primary purpose of which is to house various types of fish, the true stars of the reef tank are the corals and other creatures. <br><br>As the aquariums we maintain contain more and more diverse animal life (worms, sea appels,anemones,corals), the need for more complete additives becomes more of a necessity, and the make-up of these additives (calcium and such) has to be more geared to the new type of aquariums, in order to satisfy the requirements of all the animal life we now keep and maintain.<br><br>Water movement (by wave box for example)) is important in the reef tanks with different types of coral requiring different flow rates. Building water momentum using a gyre is an efficient method to increase flow, thus benefiting coral respiration and photosynthesis. Some corals such as the Mushroom Coral and Coral Polyps require very little light to thrive " conversely, LPS coral such as Brain coral, Bubble Coral, Elegance Coral, Cup Coral, Torch Coral, and Trumpet Coral require moderate amounts of light, and Small Polyp Stony Corals (SPS) such as Acropora Coral, Montipora, Porites, Stylopora and pocillopora require high intensity lighting. <br><br>Stony corals, which are defined by their calcerous calcium carbonate skeletons (CaCO3), are the focus of many advanced reef keepers. These corals require additional attention to water chemistry, especially maintenance of stable and optimal calcium, carbonate, and pH levels. These corals also requires additives and supplements. <br><br>A reef aquarium requires appropriately intense lighting, turbulent water movement, and more stable water chemistry than fish-only marine aquaria. Nano reefs (small tanks) are very commonly sold as complete kits which contain the tank, stand, power compact T5, T8, PL lamps or Metal Halide lighting, protein skimmer, UV sterilizer, 3 or more stage filtration, a heater and a water pump or power head. However, many Nano reef keepers decide to upgrade their aquariums with better quality equipment such as a more powerful protein skimmer or lighting. In small tanks such as Nano reef even a tiny mistake can lead to tank collapsing. <br><br>Nano reefs tanks require even more diligence with regard to water changes and attention to water chemistry because the small water capacity provides little room for error. Care must be exercised when stocking these tiny tanks because too many tenants can easily overload the tank's ability to process wastes effectively.

Revision as of 05:58, 9 March 2018

Reef tanks are usually kept at a temperature between 25 and 27 C (75-80 F). If you have any concerns about in which and how to use bubble shooter pet, you can speak to us at our web site. Reef tanks are beautiful and exotic and for some of us a piece of nature.

The mainly filtration for reef tanks usually comes from the use of great amounts of live rock which come from various rubble zones around existing reefs. Researchers and scientists find that saltwater fish tank have therapeutic health benefits. The tanks are usually constructed from either glass or acrylic.

With advances in modern tanks it's recently became possible to have a piece of coral reef at home and enjoy it in the privacy of your house without getting wet with saltwater aquarium. A reef aquarium or reef tank is an aquarium containing live corals and other invertebrates(such as snails) associated with coral reefs. Unlike the marine aquarium, the primary purpose of which is to house various types of fish, the true stars of the reef tank are the corals and other creatures.

As the aquariums we maintain contain more and more diverse animal life (worms, sea appels,anemones,corals), the need for more complete additives becomes more of a necessity, and the make-up of these additives (calcium and such) has to be more geared to the new type of aquariums, in order to satisfy the requirements of all the animal life we now keep and maintain.

Water movement (by wave box for example)) is important in the reef tanks with different types of coral requiring different flow rates. Building water momentum using a gyre is an efficient method to increase flow, thus benefiting coral respiration and photosynthesis. Some corals such as the Mushroom Coral and Coral Polyps require very little light to thrive " conversely, LPS coral such as Brain coral, Bubble Coral, Elegance Coral, Cup Coral, Torch Coral, and Trumpet Coral require moderate amounts of light, and Small Polyp Stony Corals (SPS) such as Acropora Coral, Montipora, Porites, Stylopora and pocillopora require high intensity lighting.

Stony corals, which are defined by their calcerous calcium carbonate skeletons (CaCO3), are the focus of many advanced reef keepers. These corals require additional attention to water chemistry, especially maintenance of stable and optimal calcium, carbonate, and pH levels. These corals also requires additives and supplements.

A reef aquarium requires appropriately intense lighting, turbulent water movement, and more stable water chemistry than fish-only marine aquaria. Nano reefs (small tanks) are very commonly sold as complete kits which contain the tank, stand, power compact T5, T8, PL lamps or Metal Halide lighting, protein skimmer, UV sterilizer, 3 or more stage filtration, a heater and a water pump or power head. However, many Nano reef keepers decide to upgrade their aquariums with better quality equipment such as a more powerful protein skimmer or lighting. In small tanks such as Nano reef even a tiny mistake can lead to tank collapsing.

Nano reefs tanks require even more diligence with regard to water changes and attention to water chemistry because the small water capacity provides little room for error. Care must be exercised when stocking these tiny tanks because too many tenants can easily overload the tank's ability to process wastes effectively.